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Advise individuals that: Tramadol Hydrochloride Extended-Release is for oral use only and may be swallowed complete. The capsule shouldn't be chewed, dissolved, crushed or break up. Tramadol Hydrochloride Prolonged-Launch may possibly lead to seizures and/or serotonin syndrome with concomitant usage of serotonergic brokers (which includes SRIs, NRI